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Mechanisms of disease: pathogenesis of nonalcoholic fatty liver disease

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Antigen Name:Glutathione Peroxidase 8 (GPX-8)

Experimental investigations have reported interactions with VEGFR2 phosphorylation, focal adhesion kinase (FAK) activation, ERK1/2 signaling, nitric oxide-associated pathways, and extracellular matrix regulatory networks

One example is a trial involving patients with steroid refractory pneumonitis who were randomly assigned to infliximab or IVIG alongside steroids (NCT04438382)