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Cofactor for L-methylmalonyl-coenzyme A mutase 5-Deoxyadenosylcobalamin is required by the enzyme that catalyzes the conversion of L-methylmalonyl-coenzyme A to succinyl-coenzyme A (succinyl-CoA), which then enters the citric acid cycle ( Figure 2 )

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This was followed by a decline to a median of 530 pmol/L after transitioning to weekly administration at 90 days

Possible factors include: Autoimmune diseases Liver illness Severe infections A low platelet count, also known as thrombocytopenia, signifies that the body has fewer platelets than needed for optimal clotting