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Current research has validated the regulatory effects of certain clinical medications on the Th17/Treg balance, as summarized in Table 1

The detailed biochemical mechanisms underlying the physiopathology of male infertility are not clearly understood

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Acknowledgements The authors of this work were supported financially by the Research Grants Council of Hong Hong and Tam Sai Kit Endowment Fund (Y.-C.H and K.D.K.L) and by the European Community (FP7,2007-2013) under grant agreement no