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Ryder, S

In addition, disruptions in mitochondrial Fe-S cluster biosynthesis lead to the activation of the iron starvation response, elevating intracellular iron levels and the susceptibility to ferroptosis 221,222

doi: 10.3390/ijms16035400 134 KangJELimMMBatemanRJLeeJJSmythLPCirritoJRet al

They activate multiple pathways promoting cell growth and division by maintaining oxidative stress at a controllable level, drive genetic instability and evolution, promote invasion and metastasis, and shape an immunosuppressive microenvironment (5658)

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