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Therapeutic Targets: Strategies such as mitochondrial-targeted antioxidants (e.g., MitoQ) and mitophagy activators (e.g., Urolithin A) show promise in preclinical studies

During treatment, ALT, AST, and total bilirubin should be monitored monthly for the first 3 months and periodically thereafter per label

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Lewy bodies in the lateral hypothalamus: do they imply neuronal loss

To address this challenge, Xia and coworkers designed and synthesized rationally sequenced, targeted lycopene nanodots, which facilitate neural enrichment and mitochondrial regulation of lycopene via BBB transcytosis and neuronal mitochondria-targeting capabilities