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The E factor 25 years on: The rise of green chemistry and sustainability

Oxidation of plasma cysteine/cystine and GSH/GSSG redox potentials by acetaminophen and sulfur amino acid insufficiency in humans

Some of these, including many neuropsychiatric drugs (e.g., SSRIs, SNRIs, amitriptyline & other TCAs, trazodone or nefazodone, gabapentinoids, (ar)modafinil, and Abilify), along with dihydropyridines (a subset of calcium channel blockers), fludrocortisone, midodrine, and cognitive behavioral therapy (CBT), all had over 20% of patients responding negatively