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Cancer Causes Control 15: 977985

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ATO induces significant oxidative DNA damage in normal skin fibroblasts, triggering the ATM- Ataxia-Telangiectasia and Rad3-Related (ATR)-Chk checkpoint pathway and leading to cell cycle arrest [316]

When looking at weight loss thresholds, 78% of patients on tirzepatide achieved at least 15% weight loss, compared to 51% with semaglutide