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This highlighted the urgent need for novel therapeutic approaches that aims at preventing and/or reversing its sequelae (Zhao et al., 2018)

Rosa DD, Pasqualotto AC, Denning DW

Alpha-lipoic acid supplement in obesity treatment: A systematic review and meta-analysis of clinical trials

Thus, the complex role of ROS in T-cell biology can be simplified by dividing it in two parts: (i) the effects of large exogenous quantities of ROS, known as oxidative stress, and (ii) the function of compartmentalized, dose- and time-controlled endogenous ROS (hereafter referred to as signaling ROS)