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Adults that declined (vs enrolled) were temporally closer to time of LT (21.9 mo vs 38.9 mo, p =0.049), more frequently had comorbid psychiatric diagnosis (36.4 vs 7.1%, p =0.006), and history post-LT of slip or relapse (39.1 vs 14.6%, p =0.01)

Marins 3 , Kaili Ren 3 , Marco Vilela 3 , Thikshaya Mahendran 4 , Amanda Sees 2 , May Hagiwara 3 and Rohit Loomba 5 , (1)University of Florida, Gainesville, FL, USA, (2)Iqvia, Plymouth Meeting, PA, USA, (3)Takeda Development Center Americas, Inc., Cambridge, MA, USA, (4)Iqvia, Bengaluru, India, (5)University of California, San Diego, San Diego, CA Background: Diagnosis (dx) of alpha-1 antitrypsin deficiency (AATD)-associated liver disease (LD) is challenging due to the variable risk and asymptomatic nature of the disease

Kanbay, M

The major detoxification pathway of 4HNE involves GSTs 16

Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes