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S8A, cells were fixed with PTEMF buffer (20 mM PIPES pH 6.8, 0.2% (v/v) Triton X-100, 10 mM EGTA, 1 mM MgCl 2 , 4% PFA (wt/v) in PBS) for 12 min at room temperature

Additionally, their low molecular weight allows for rapid clearance from the bloodstream, reducing the risk of organ accumulation

The results showed that both polyphenols, at lower concentrations than 5-ASA, activated Nrf2, increased HO1 and glutamate cysteine ligase mRNA expression, enhanced the reduced-to-oxidized glutathione ratio, and inhibited reactive species production, with resveratrol and 5-ASA also increasing nuclear PPAR- levels

doi: 10.3389/fimmu.2024.1407237 27 JalinkMde BoerECWEversDHavingaMQVosJMIZeerlederSet al