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Herein, the optimization pathways of existing therapeutics and emerging therapeutic directions are systematically reviewed, with particular emphasis on their mechanisms of action, current clinical application status, and future potential, with the aim of providing guidance for personalized IBD management

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Preparation Synthesis of 5-Amino-1-methyl-1-quinolinium Iodide(NNMTi): Iodomethane (0.160 ml, 0.365 g, 2.6 mmol) was added to a solution of 5-aminoquinoline (0.277 g, 1.9 mmol) in tetrahydrofuran (7 ml), and stirred at room temperature for 1 day until a red solid precipitated