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Hypoxia-induced changes in endothelial cell phenotype and function

Additional information showed that colonic bacteria might metabolize primary bile acids into toxic bile salts that are then absorbed through the ulcerated colon into the portal circulation, but no evidence of bile acid metabolism abnormalities in patients with PSC or CUC has been found (Siegel et al, 1977)

Some bacteria found increased in T2D patients, such as Prevotella copri and Bacteroides vulgatus , were able to advance insulin resistance and increase availability of branched chain aminoacids in mice