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In contrast, OCTN1-mediated transport of zwitterionic substrates (e.g., EGT) displays distinct kinetic and regulatory features

Of note, fatigue is one of the most devastating, unexplained symptoms of sarcoidosis itself, but it can be exacerbated by its treatment, and can also be associated with withdrawal of GCs [20,21]

The most severe cases tend to exhibit elevated levels of plasma glucose (Freire Jorge et al., 2017), triglycerides (Lee et al., 2015), and lactate (Nichol et al., 2010

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In contrast, ChiE showed two reactive thiols in the reduced form and 0.5 in the oxidized form, consistent with reversible redox switching of C156 and C227 within the hydrophobic pocket