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Cells were seeded into a 96-well plate (100 l/well, 3103 cells/well) and the plate was incubated overnight under 5% CO2 at 37C

25, 38 As aberrations in the TP53 gene and t(4:14) translocations are seen in 15% of patients 49 and correlated with short progression-free survival and resistance to alkylating agents at relapse, 50 the ability of BSO to sensitize MM cells with this phenotype suggests that BSO+L-PAM may have clinical activity in the most aggressive forms of MM

Recently, it has been suggested that oxidative stress is an important contributing factor to hepatotoxicity induced by long-term OXA chemotherapy (9,10)

L-serine: a neglected amino acid with a potential therapeutic role in diabetes

They may suggest updated lab work to guide the next phase of your plan