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Several patients have had retinitis pigmentosa and severely abnormal electroretinograms, indicating disturbed retinal physiology (71

Microb Cell Fact 12:110

A6 cells were maintained in 75 % NCTC-109 supplemented with 10% FCS and 2 mM glutamine at 27C and 5% CO2 as above

Statistical analysis of mutant inactivation was performed using a t-test between the reduced activity of the unmodified enzyme, normalized as 100%, and the percentage of reduced activity measured following incubation with GSSG or H 2 O 2