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Distinct immune cells, including monocytes, macrophages, and T cells, extracted from patients suffering from HUA, are observed to undergo cellular activation and enhanced migratory effects, increased cytokine production, and problematic cellular differentiation when stimulated by urate in vitro

doi: 10.1371/journal.ppat.1007393 56 LodesMJYoshinoTP

Intriguingly, higher AIMP3 expression was associated with better survival in gastric and colon adenocarcinoma, but with poor survival in breast, lung, and liver cancers 101

But, how does it specifically help men, and what happens when your levels run low