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In silico modeling of the proposed PKC-Pin1 complex Using the Swiss-PdbViewer package (23), we modeled the complex of the WW domain of Pin1 with PKC using the structure of another Pin1 complex as a template

Targeting GPX4 restores ferroptosis, enhances the efficacy of BRAFi EGFRi, and overcomes resistance in in vitro, in vivo, organoid, and patient-derived xenograft models