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This disruption initiates a critical sequence of events: it promotes the phosphorylation of p53 and facilitates its translocation to the cytoplasm

Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice

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Some assay formats also carry risk of misleading readouts when compounds interact with reporters, dyes, membranes, plastics, or plate surfaces, creating signals that appear pathway related but are driven by assay chemistry