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Jin X, Yu H, Zhang Z, Cui T, Wu Q, Liu X, et al

Furthermore, epigenetics play a role in influencing risk factors for CVD, including but not limited to age, hypertension, smoking, excessive alcohol consumption, and diabetes

Korsgaard N, Aalkjaer C, Heagerty AM, Izzard AS, Mulvany MJ

indicates that lactate upregulates the expression of NUSAP1 through lysine lactylation modifications, thereby forming a NUSAP1-LDHA-glycolysis-lactate conduit loop