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During the past 50 years, attempts to establish suitable three-dimensional in vitro cell culture models to mimic in vivo processes have gained more attention

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Granulosa cells play a crucial role in maintaining the redox balance of oocytes, and an increase in granulosa cell apoptosis may lead to oxidative stress in oocytes (Figures 4CE), indicating oxidative stress in oocytes of the hypo group

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27 We also found that FBX8 inhibited the proliferation, invasion and metastasis of CRC by promoting the degradation of GSTP1