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The difference between cagrilintide and survodutide lies in receptor selectivity: amylin-only versus dual incretin-glucagon activation, determining whether the compound affects gastric motility alone or modulates systemic glucose and lipid metabolism

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N Engl J Med 335:13631367 Amselem S, Duquesnoy P, Attree O, Novelli G, Bousnina S, Postel-Vinay MC, Goossens M (1989) Laron dwarfism and mutations of the growth hormone-receptor gene