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At the microbial level, taxa such as Lactobacillus and Bifidobacterium favour TRP availability for 5-HT synthesis, whereas enrichment of pro-inflammatory Proteobacteria enhances immune-driven IDO activation and KYN production [175], directly linking microbial ecology to mood-relevant neurochemical pathways

The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody

Tsuchiya M, Miura T, Hanaoka T, Iwasaki M, Sasaki H, Tanaka T, Nakao H, Katoh T, Ikenoue T, Kabuto M, Tsugane S

35 reported that the plasma concentration of citrulline (which is exclusively synthesized from glutamine and proline by enterocytes in most mammals including humans and pigs) was a reliable marker for the mass and metabolic activity of the small bowel in short bowel patients

10.1097/SHK.0b013e3182655932 166