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AOD 9604 and Semaglutide Semaglutide is an FDA-approved glucagon -like peptide-1 receptor agonist (GLP-1 RA) that is sold in the market under 3 different brand names

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grants BO996/7-1 and SCHL615/3-1 to CB and US), the Interdisciplinary Center for Clinical of Research (IZKF) of the Universittsklinikum Erlangen (project A87 to US) and the Collaborative Research Center CRC1181 (DFG, project C04 to US and CB)

Inhibited endogenous H2S generation and excessive autophagy in hippocampus contribute to sleep deprivation-induced cognitive impairment

In contrast, pharmacological activation by CB1 agonists reduced the hormonal response to stress, indicating that the endocannabinoid system modulates the HPA axis (Patel et al., 2004)