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The zebrafish has emerged as a particularly valuable model for deciphering this complexity and screening therapeutic candidates, as it allows for the rapid establishment of pathology through various dietary and chemical means that recapitulate key features of human MASLD

One of the most commonly used toxins to model response and sensitivity to oxidative damage in mitochondria is the bipyridyl herbicide paraquat (PQ 2+ ) 14,15

10.1016/j.tcb.2007.07.009 Trends Cell Biol

However, others can be serious and affect your long-term health

When NAD levels drop with age, your brain becomes especially vulnerable to energy deficits