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Referring to the tissue distribution of silymarin it can be concluded from different studies in patients with colorectal carcinoma and studies in mice [34] that the highest tissue [35] concentration was found in the colon [36] whereas the lowest concentration was detected in the brain and the prostate [35, 37]

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[DOI] [PubMed] [Google Scholar] 28.Michelon M., Huang Y., de la Torre L.G., Weitz D.A., Cunha R.L

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