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Intrinsic and extrinsic factors in skin ageing: a review

In cardiac cells, UQCRC1 prevents ischemia/reperfusion injury by activating the PI3K/Akt/GSK-3 pathway, upregulating the anti-apoptotic protein Bcl-2, and downregulating the pro-apoptotic protein Bax (Yi et al., 2020)

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Conversely, defective autophagy exacerbates inflammatory responses, further aggravating insulin resistance in women with PCOS ( 3.3 Ferroptosis Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, may play a key role in the pathogenesis of PCOS

Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes