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Novel delivery systems: advances and persistent limitations Recent advances in gene therapy have focused on engineered viral vectors [117]

Vitamin B12 is used to treat pernicious anemia and vitamin B12 deficiency

55 Thus, a concentration of 35 M will inhibit 99.9% of the activity of HPD

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Compounding these effects is the disruption of neuroendocrine signaling along the hypothalamic-pituitary-ovarian (HPO) axis, which further destabilizes reproductive function