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PFD's therapeutic effects on IPF involve the antioxidant mechanism of suppressing BACH1 and enhancing NRF2

demonstrated that macrophages can absorb extracellular lactate to promote the lactylation of high mobility group box-1 (HMGB1), which is subsequently secreted via exosomes, increasing endothelial permeability and inducing further endothelial barrier dysfunction [163]

Notably the association between GGT and cardiovascular mortality was not significant in the subgroup of Asian participants [relative risk =1.76 (0.763.30)] (36)

Andrew Huberman: What are some cold protocols that you find particularly interesting or attractive from the standpoint of, I don't know, pick your favorite, metabolism, neuro/mood effects, brown fat stimulation, which, of course, weaves back to metabolism

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