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However, other pathophysiological modifications within melanoma cells may contribute to therapy resistance [4, 5], demanding for large-scale computational models to simulate the complex physiology of a tumour in an integrated manner and comprehensively foster the identification of alternative therapeutic vulnerabilities applying high throughput in silico approaches [6, 7]

PMID: 106 HayashimaKKatohH

Saitoh et al

These transporters were highly abundant in AML cell lines whereas the majority of other ABC transporters was expressed at moderate or low levels (Supplementary Fig