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A functional summary of the top 100 non-HLA AS associated genes currently listed on Open Targets database of genetic associations with disease show 95 are also common to psoriasis, UC, and Crohns (Table 2) [31, 42]

2014;111:E448593

Kannt A, Rajagopal S, Kadnur SV, Suresh J, Bhamidipati RK, Swaminathan S, Hallur MS, Kristam R, Elvert R, Czech J, Pfenninger A, Rudolph C, Schreuder H, Chandrasekar DV, Mane VS, Birudukota S, Shaik S, Zope BR, Burri RR, Anand NN, Thakur MK, Singh M, Parveen R, Kandan S, Mullangi R, Yura T, Gosu R, Ruf S, Dhakshinamoorthy S (2018) A small molecule inhibitor of nicotinamide N -methyltransferase for the treatment of metabolic disorders

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