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Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM et al (2013) Pharmacologic inhibition of ROCK2 suppresses amyloid- production in an Alzheimers disease mouse model

Furthermore, physical exercise intensifies these advantageous outcomes by fostering angiogenesis, facilitating mitochondrial biogenesis, and promoting anti-inflammatory signaling, thus reinforcing the critical crosstalk between muscle and vasculature necessary for optimal aging