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(iii) weaken or strengthen protein interactions with its biological counterparts/binding partners

Investigational agents involving the ISR in current ALS clinical trials target the eIF2 complex, PP1R15A, and pathological RAN translation (Table 3)

Gustin, S

Poult Sci

Materials and methods Subject population Parents of patients seen from 20082011 in a medically based autism clinic were requested to consent to allow their childs medical information to be anonymously abstracted into a clinical database that contained medical history, physical examination findings and the results of neurological and metabolic testing