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Funding This work was supported by Parkinson Foundation CSRA Chapter PSG00026, Parkinson Foundation CSRA Chapter PSG00028, Augusta University Intramural Grants Program PSRP00075, and VA Merit Award RR&D N1613-I

Western blot, followed by densitometry analysis, revealed a significant decrease in SIRT1 protein levels in the AMD RPE as compared to normal RPE (Fig