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High doses of vitamin E in the treatment of disorders of the central nervous system in the aged

Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue

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Discussion Our study uncovers how NOTCH1 mutations reprogram mitochondrial metabolism in CLL, establishing a mechanistic connection between oncogenic signaling and metabolic plasticity