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High-throughput sequencing (HTS) data quality can be compromised by sequencing errors, sampling bias, and variable 16S copy number across taxafactors that skew abundance and diversity estimates (Kembel et al., 2012

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From an in silico analysis of ebselen bound to the main protease Mpro of SARS-CoV-2, the Se atom of the open structure of ebselen establishes a covalent interaction with the Mpro catalytic cysteine-145 (see Fig