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The 6-TGN under-production in a subgroup of IBD patients is largely believed to be due to thiopurine hypermethylation ( shunters ) whereby thiopurine compounds are preferentially metabolized into methyl-mercaptopurine (meMP) and meMPR ( Figure 1 ), resulting in inadequate 6-TGN levels and therefore treatment resistance (Hindorf et al., 2004)

Cx43 is a tumor suppressor, and AKAP95 functions to promote tumor growth 27

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A certain amount of acetaminophen is not conjugated with glucose and is further metabolized to the highly reactive NAPQI intermediate, resulting in the formation of the glutathione conjugate

What are the signs of a vitamin B12 deficiency that may require injections