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Understanding these potential mechanisms helps clinicians and patients identify strategies to minimise discomfort whilst maintaining adequate B12 intake

Clinical research has generally demonstrated favorable tolerability, though individual responses vary

cutaneous = skin), which is considerably looser in the dog than in the human

Lipolytic actions of leptin are dependent on the leptin receptor, since obese fa/fa Zucker rats (112) and db/db mice (32) that have an inactivating mutation of the long form of the leptin receptor are resistant to leptin-induced lipolysis

This can lead to challenges with fertility and testicular health if left unaddressed