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Description

C2 is 20-fold more selective at human FFAR2 than at human FFAR3, while it is equipotent at both mouse orthologs

Lancet 349 , 14361442 (1997)

Baruah and J

2112 As for all non-steroidal anti-inflammatory drugs the pharmacodynamic effects of diclofenac sodium are of anti-inflammatory, analgesic and antipyretic character due to the decrease of the prostaglandin synthesis from arachidonic acid by inhibition of the cyclo-oxygenase activity