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A study demonstrated that alterations in phosphatidylcholine (PC) metabolism in ARDS patients correlated with increased inflammation and oxidative stress, 50 resulting in more severe lung injury and lower levels of surfactant PC species, which contribute to alveolar collapse and heightened inflammation 51 (Figure 2)

Q.ShangK.QinC.et al (2021)

MATER protein expression and intracellular localization throughout folliculogenesis and preimplantation embryo development in the bovine

The production of NADPH is elicited under oxidative stress conditions as a compensatory mechanism to provide for the increased necessity of reducing equivalents [55,74]

In most cells, glutathione is found at concentrations of 1-10 mM in the cytoplasm and at lower concentrations in subcellular organelles, including the nucleus, mitochondria, and endoplasmic reticulum