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Peng J, Jury EC, Donnes P, Ciurtin C

The first meta-analysis was published in 2012 and featured 15 studies (n=360 subjects) with an overall outcome of beta-alanine improving the exercise outcome measures compared to control (p=0.002 with an overall effect size (ES) of 0.374) and the majority of the performance effects being demonstrated over 1 to 4 min of high-intensity exercise (Hobson, Saunders, Ball, Harris, & Sale, 2012)

Posteriormente, el pptido purificado se trata con una sal de cobre (como el sulfato de cobre) en un proceso llamado quelacin, donde el ion cobre se une fuertemente al pptido, formando el complejo peptdico de cobre