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Recent work has uncovered parallel MAPK activation pathways operating through farnesylation-independent mechanisms in mature adipocytes, highlighting the complexity of these signaling networks (196)

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35 A population pharmacokinetic analysis indicated that when AL concentrations are at steady state, delays in the scheduled injection interval of up to 4 weeks resulted in minimal decreases in median aripiprazole plasma concentrations

, NLR family pyrin domain containing 3 (NLRP3)) that sense pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs), such as the accumulation of ROS or the efflux of potassium ions (K + )