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Two enzymes related to ferroptotic lipid metabolism were found through the haploid gene screening of chronic myeloid leukemia cell line KBM7 cells: acyl-CoA synthetase (a long-chain family member 4 (ACSL4) for synthesizing Pes), and lysophosphatidylcholine acyltransferase 3 (LPCAT3) for lipid remodeling