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As part of the erythrocyte antioxidant system, Prx2 is responsible for the removal of low H 2 O 2 concentrations, since the Trx system has a limited capacity for Prx2 regeneration into its reduced active form [32, 59, 60, 73]

pmid:25039836

Similarly, post-inflammatory hyperpigmentation (PIH) is common in dark skin, and dark patches of skin can develop after an injury, inflammatory response, or laser treatments

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