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If it happens once in a while, it may be a rough week, not a long-term problem

The NHS and NICE Clinical Knowledge Summaries recommend established treatments with proven efficacy and safety profiles

If the patient has to be outside in the sun, using sunscreen and covering up bare skin whenever possible is very helpful

Initial cranial imaging ruled out multiple sclerosis and stroke

A further possible mechanism is that naevomelanocytes originate from neural crest cells destined to become melanocytes in the oral epithelium, but for reasons unknown remain entrapped in the submucosa