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At 100+ pounds of loss, the skin has been dramatically stretched for years and the damage to collagen and elastin networks is more extensive

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You dont want to just be in the reference range, the optimal range for B12 is much higher and ideally, you want to be above 400, and there does not seem to be an upper limit or toxicity from high Vitamin B12 levels

The quantity of growth hormone matters less than the timing and amplitude of the signal

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