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IL-18, another proinflammatory cytokine released when the NLRP3 inflammasome is activated, has been demonstrated to be correlated with susceptibility to sporadic late-onset AD (92,96)

Front Psychiatry 12:742058 Pinard E, Borroni E, Koerner A, Umbricht D, Alberati D (2018) Glycine transporter type I (GlyT1) inhibitor, bitopertin: a journey from lab to patient