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J Med Chem 2004

10.1523/jneurosci.19-18-07699.1999 142 MiddeN

Normal variation includes: Slight colour differences Moving vs stuck pucks Minor shrinkage Texture variation However, contact support if you observe: Visible moisture inside the vial Wet or partially dissolved material Severe discolouration beyond normal variation Damaged stoppers or cracked vials Moisture is the true threat not puck movement

(Frontiers in Pharmacology, 2022) reported pharmacokinetics and tissue distribution in rats and dogs, including a rapid plasma half-life under 30 minutes after IM or IV dosing

Discard reconstituted vials that look cloudy, develop particulates, or have changed color significantly beyond the expected blue tint