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10.1523/jneurosci.23-01-00269.2003

These changes drive T cells toward senescence, a state of irreversible cell cycle arrest accompanied by the senescence-associated secretory phenotype, characterized by inappropriate activation, poorer function and enhanced secretion of proinflammatory cytokines such as IL-6, TNF-, and IFN- (Olivieri et al., 2018

AM-V acknowledges Consejo Nacional de Humanidades, Ciencias y Tecnologas (CONAHCyT) for her doctoral scholarship (CVU: 629783)

As one of the most evolutionarily conserved lifespan-extending strategies, dietary restriction has emerged as a promising intervention for promoting healthy aging