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Endothelial dysfunction (ED) occurs as a result of the impairment of EC regulatory functions and is linked to the development of many diseases including atherosclerosis, hypertension, liver diseases, diabetes, and even COVID-19 [11, 16,17,18,19,20]

The protein expression of the IL-36 agonist was verified by immunohistochemical labeling and increased mRNA expression of IL-36 cytokines, particularly IL-36Ra, in psoriatic skin lesions in various cells such as keratinocytes, endothelial cells, dermal fibroblasts, dendritic cells, and CD68 + macrophages

When l-carnitine enters the brain, it supports the production and synthesis of acetylcholine, which is a neurotransmitter that plays a key role in learning and memory

Over control, PSII activity recorded a significant downregulation by 38.72% under Al exposure which was recovered by 25.24% under Al + MT treatment (Fig