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In men, excess adiposity is associated with decreased testosterone, increased estradiol from aromatization, impaired spermatogenesis, and erectile dysfunction

Use of energy crop ( Ricinus communis L.) for phytoextraction of heavy metals assisted with citric acid

The involvement of p90RSK-NRF2 signaling in HIV accelerates the aging process by regulating four components of the senescent phenotype: (1) DNA damage caused by telomere shortening, leading to the induction of p16 and p21, (2) generation of ROS, (3) inflammation, and (4) impairment of efferocytosis induced by antiretroviral therapy [116]

conversely, the overexpression of SCL7A11 enhance cell resistance to ferroptosis, which is also one of the reasons for drug resistance in tumor cells (Huang et al., 2005

Amino acid transport defects in human inherited metabolic disorders